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The Ohio State University

Global Infectious Disease Research

Wednesday, April 23, 2014
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Philip R.O. Payne, Ph. D.

(614) 293 - 7203
Associate Professor
Chair of Biomedical Informatics
Biomedical Informatics
M.S., Applied Medical Informatics
Ph.D., Biomedical Informatics
Additional Information: 

Dr. Payne is currently appointed as an associate professor in the Department of Biomedical Informatics at The Ohio State University (OSU-BMI). He also serves as the Director of the Biomedical Informatics Program for OSU’s CTSA-funded Center for Clinical and Translational Science, Co-Director of the Biomedical Informatics Shared Resource within the OSU Comprehensive Cancer Center, and Co-Director of the OSU Center for IT Innovation in Healthcare (CITIH). Dr. Payne received his Ph.D. with distinction in Biomedical Informatics from Columbia University, where his research focused on the design and evaluation of advanced information management platforms for clinical and translational research. Dr. Payne’s research portfolio is actively supported by a combination of NCRR, NLM, and NCI awards and contracts. Current projects within Dr. Payne’s laboratory include: 1) the development of novel informatics platforms capable of enabling the collection, exchange, and integration of distributed, multi-dimensional, and heterogeneous biomedical data and knowledge sources; 2) the use of knowledge engineering methodologies to support high-throughput discovery of novel phenotype-biomarker linkages and complexes in large-scale data sets; and 3) the application of workflow analysis and human-computer interaction design principles in order to enable the adoption and optimal use of information systems in biomedical research and clinical care settings. Publications:

  1. Saltz J, Hastings S, Langella S, Oster S, Kurc T, Payne PR, Ferreira R, Plale B, Goble C, Ervin D, Sharma A, Pan T, Permar J, Brezany P, Siebenlist F, Madduri R, Foster I, Shanbhag K, Mead C, Chue Hong N. A Roadmap for caGrid, an Enterprise Grid Architecture for Biomedical Research. Stud Health Technol Inform 2008; 138:224-37.
  2. Erdal S, Catalyurek U, Payne PR, Saltz J, Kamal J, Gurcan M. A knowledge-anchored integrative image search and retrieval system. J Digit Imaging 2008; 22(2):166-82.
  3. Payne PR, Borlawsky T, Kwok A, Dhaval R, Greaves A. Ontology-anchored Approaches to Conceptual Knowledge Discovery in a Multi-dimensional Research Data Repository. AMIA Translational Bioinformatics Summit Proc. 2008.
  4. Payne PR, Borlawsky T, Kwok A, Greaves A. Supporting the Design of Translational Clinical Studies Through the Generation and Verification of Conceptual Knowledge-anchored Hypotheses. AMIA Annu Symp Proc. 2008.
  5. Xiaodan S, Lucas D, Liwen Z, Davis M, Knapp A, Young D, Payne PR, Parthun M, Marcucci G, Grever M, Byrd J, Freitas M. Validation of an LC-MS Based Approach for Profiling Histones in Chronic Lymphocytic Leukemia. Proteomics. 2009; 9(5):1197-1206.
  6. Hastings S, Oster S, Langella S, Melean C, Borlawsky T, Dhaval R, Payne PR. Adoption and Adaption of caGrid for CTSA. AMIA Translational Bioinformatics Summit Proc. 2009.
  7. Borlawsky T, Dhaval R, Hastings S, Payne PR. Development of an Agile Knowledge Engineering Framework in Support of Multi-Disciplinary Translational Research. AMIA Translational Bioinformatics Summit Proc. 2009.
  8. Payne PR, Kwok A, Dhaval R, Borlawsky T. Conceptual Dissonance: Evaluating the Efficacy of Natural Language Processing Techniques for Validating Translational Knowledge Constructs. AMIA Translational Bioinformatics Summit Proc. 2009.
  9. Embi PJ, Payne PR. Clinical Research Informatics: Challenges, Opportunities and Definition for an Emerging Domain. J Am Med Inform Assoc. 2009 May-Jun; 16(3):316-27.
  10. Payne PR, Embi PJ, Sen CK. Translational Informatics: Enabling High Throughput Research Paradigms. Physiological Genomics. 2009. (Invited Submission, In Press)
  11. Embi PJ, Payne PR. The Role of Biomedical Informatics in Facilitating Outcomes Research: Current Practice and Future Directions. Circulation. 2009. (Invited Submission, In Press)
  12. Kundu A, Ozer HG, Borlawsky T, Keen-Circle K, Huang K, Payne PR. Clinical Attribute Network for Chronic Lymphocytic Leukemia. Proceedings IEEE International Conference on Bioinformatics & Biomedicine. 2009. (In Press)
  13. Pressler TR, Binkley PF, Payne PR. Building Bridges: Making Statistical Issues Accessible to the Biomedical and Translational Researcher. Joint Statistical Meetings Proc. 2009. (In Press)


  1. Borlawsky T, Greaves A, Kwok A, Payne PR. TOKEn: Translational Ontology-anchored Knowledge Discovery Engine. AMIA Translational Bioinformatics Summit Proc. 2008.
  2. Kamal J, Borlawsky T, Erdal S, Liu JF, Payne PR. ASAP: A Data-driven Advanced Screening Tool for Active Clinical Protocols. AMIA Spring Congress Proc. 2008.
  3. Payne PR, Kwok A, Greaves A. Integrating Web Portlet Technologies with caGrid to Enable Rapid Application Development: the CRC Patient Study Calendar. AMIA Annu Symp Proc. 2008.
  4. Kamal J, Silvey S, Buskirk J, Dhaval R, Erdal S, Ding J, Ostrander M, Borlawsky T, Payne PR. Innovative Applications of an Enterprise-Wide Information Warehouse. AMIA Annu Symp Proc. 2008.
  5. Borlawsky T, LaFountain J, Petty L, Saltz J, Payne PR. Leveraging an Existing Data Warehouse to Annotate Workflow Models for Operations Research and Optimization. AMIA Annu Symp Proc. 2008.
  6. Dhaval R, Borlawsky T, Ostrander M, Santangelo J, Kamal J, Payne PR. Implementation of a Metadata Architecture and Knowledge Collection to Support Semantic Interoperability in an Enterprise Data Warehouse. AMIA Annu Symp Proc. 2008.
  7. Ding J, Erdal S, Borlawsky T, Liu J, Golden-Kreutz D, Kamal J, Payne PR. The Design of a Pre-Encounter Clinical Trial Screening Tool: ASAP. AMIA Annu Symp Proc. 2008.
  8. Payne PR, Borlawsky TB. Development of an Agile Data-Anchored Workflow Modeling Methodology. AMIA Annu Symp Proc. 2009. (In Press)
  9. Dhaval R, Hastings S, Melean C, Borlawsky TB, Payne PR. Development of an Extensible Knowledge Management Infrastructure for the Translational Research Informatics and Data Management Grid (TRIAD). AMIA Annu Symp Proc. 2009. (In Press)
  10. Finneran C, Rice R, Xu D, Stevens G, Laucher C, Smaltz H, Payne PR, Kamal J. A Collaborative Research Portal for Clinical and Translational Science. AMIA Annu Symp Proc. 2009. (In Press)